Retinal Nerve Fiber Layer-to-Disc Ratio Distinguishing Glaucoma from Nonarteritic Anterior Ischemic Optic Neuropathy

Purpose: To evaluate the diagnostic value of retinal nerve fiber layer-to-disc ratio (RDR) compared to established parameters including layer thickness (RNFLT), Bruch membrane opening-minimum rim width (BMO-MRW), and area (BMO-MRA) for differentiating between open angle glaucoma (OAG) nonarteritic anterior ischemic optic neuropathy (NAION).Methods: This retrospective study included 23 disc size-matched normal control eyes OAG NAION matched according global RNFLT. The RDR, RNFLT, BMO-MRW, BMO-MRA were analyzed; capabilities these using under receiver operating characteristic curve (AUC).Results: BMO-MRW total lower in group than other two groups (all <i>p</i> < 0.001). RDR was greatest group, followed by healthy (<i>p</i> Between groups, AUCs temporal inferior BMO-MRA, 0.987, 0.996, 1.000, respectively; greater RNFLT (0.811; = 0.005, 0.006, respectively).Conclusions: could be one useful differential diagnosis NAION.